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IUSM Scope

August 12, 2011
Volume 15 Number 31 • Indianapolis, Indiana

Topics this issue:

Above the Fold

Arrow IUSM to welcome largest incoming class

The IUSM Class of 2015 will don a physician’s white coat Saturday, Aug. 13, in a ceremony at the Murat Theatre, 502 N. New Jersey St., which marks the beginning of an intense four-year curriculum.

The incoming 328-member class is the largest in the medical school’s history. They will gather with friends and family at 3 p.m. for the White Coat Ceremony, an annual rite of passage. Keynote speaker Lisa Harris, MD, chief executive officer and medical director of Wishard Health Services, will present “We’re All in This Together.”

Following Dr. Harris’ remarks, the students will cross the stage and be assisted by a medical school faculty member into a white coat. The students then recite in unison a physician’s pledge whose origins are attributed to the Greek physician Hippocrates.

For more information, visit the IUSM Newsroom.


Arrow Sculpture installation marks new eye center

Installation began Friday, Aug. 12, on a large work of public art by renowned sculpture Don Gummer, who attended Ben Davis High School and the Herron School of Art before making his home in New York and Connecticut. Titled “Open Eyes,” the piece will anchor the green space to the east of the institute. 

The installation precedes several events marking the completion of the $30 million, 77,000-square-foot advanced vision science center. Friday, Aug. 19, the new center will host the second annual Eugene and Marilyn Glick Eye Institute Vision Research Symposium from 7:30 a.m. to 1 p.m., in its Spitzberg Conference Room, followed by a dedication ceremony, including IU President Michael McRobbie, at 3 p.m. in the IUPUI Campus Center.

Saturday, Aug. 20, Glick Eye Institute will be open to the community, including free health screenings, building tours and art projects for children, including sidewalk chalk, drawing and face-painting.

For more information, visit Questions to


Arrow Global health receives endowment

The newly-formed IU Center for Global Health has received its first endowed faculty position. The Donald E. Brown Professorship in Global Health was established with a gift of $1.5 million from Donald E. Brown, MD, an IU alumni and software entrepreneur.

Dr. Brown is co-founder and CEO of Interactive Intelligence, a global provider of IP business communications software and services. In 2007, Dr. Brown gave $1 million to the Indiana-Kenya Partnership/AMPATH, which is coordinated by the IU Center for Global Health. This new gift builds on his commitment to supporting global health programs.

Robert Einterz, MD, associate dean for global health, director of the IU Center for Global Health and professor of clinical medicine at IUSM, will be the first to hold the endowed position, which will be used to support faculty leading global health programs that aim to eliminate health disparities by advancing global health research and education and delivering health-care services to underserved populations across the globe.

For more information, visit the IUSM Newsroom.


Arrow Cancer center earns certification

IU Simon Cancer Center hematology oncology team has received recognition from the world's leading oncology society for achieving the highest levels of quality for the care provided to its patients.

The multidisciplinary team is the first oncology group in central Indiana to achieve the three-year certification from the Quality Oncology Practice Initiative (QOPI) Certification Program, an affiliate of the American Society of Clinical Oncology (ASCO). QOPI is a voluntary self-assessment and improvement program.

For more information, visit


Arrow Public and Media Relations changes

The IUSM Office of Public and Media Relations has merged with the IUPUI Office of Communications and Marketing, the IU Office of Creative Services, the IU Bloomington communications office and the IU President’s communications office as part of IU Public Affairs and Government Relations. 

The new PAGR organization aims to consolidate and reorganize various functions and talent to better serve the communications and marketing needs of IUPUI and the medical school and their faculty, students and staff.

You can still find us on the Web at

To learn more about the full complement of services and resources provided by PAGR, visit


Faculty Development & News

Arrow New Faculty Orientation — Aug. 17

The IU School of Medicine New Faculty Orientation is scheduled for Wednesday, Aug. 17. Faculty members hired after Aug. 15, 2010 should plan to attend the 2011 School of Medicine and IUPUI New Faculty Orientation events. Meet the dean and connect to resources at the IUSM New Faculty Luncheon on Aug. 17 before attending the IUPUI New Faculty Welcome.

For registration information and additional program details, visit

Questions to


Arrow Faculty Steering Committee meeting

The School of Medicine's excellence hinges on the engagement and vitality of its faculty, and the work of the Faculty Steering Committee plays a crucial role in this regard. The FSC is the principal representative body of the faculty and its collaboration with school administration, the campus and the university.

We are attempting to enhance the quality of communication between members of the faculty and the FSC, and to enhance the FSC's contribution to the work of our school. The FSC meets monthly for 90 minutes. The next meeting is at noon Thursday, Aug. 18, in Daly Center 186. These meetings are open to all faculty members.

The membership of the FSC, minutes of past meetings and the agenda for the upcoming meeting are posted at

Please take a moment to familiarize yourself with the work of the FSC and share with me or any of our other representatives any concerns or opportunities you feel our faculty should be addressing.

Richard Gunderman, MD
IUSM Faculty President


Student Showcase

Arrow Family medicine student luncheon

The Department of Family Medicine will host a lunch for all interested MS1 students from noon to 12:45 p.m. Thursday, Aug. 18, in the IUPUI Campus Center.

This event is an opportunity for first-year medical students to meet and talk to faculty members in the Department of Family Medicine. Lunch will be available first come, first serve. Door prizes (ICM-II texts) will be available.


Events & Lectures

Arrow Life Sciences Lunch Series — Aug. 16

The topic for August will be “Antibiotics and Infection Control: A Dose of Innovation for Serious Public Health Challenges” with presentations by Laurie Rish, RN, BSN, director of infection prevention at IU Health, Eric Utt, PhD, director of worldwide policy at Pfizer Inc., and Kristin Jones, president and CEO of Indiana Health Industry Forum.

The presentations on Tuesday, Aug. 16, are from noon to 1 p.m.; registration begins at 11:30 at Barnes & Thornburg LLP, 11 S. Meridian St., Indianapolis. Video conferencing also is available. The event is sponsored by Hoosiers Work For Health.

For more information, contact Kristin Jones at 278-9973 or


Arrow Women's health webinar series

The IU National Center of Excellence in Women’s Health and the IU Simon Cancer Center will present the next lecture in their 10-part multi-disciplinary breast health webinar series from 4 to 5 p.m. Wednesday, Aug. 17, with a discussion on patient advocacy by Robert Goulet, MD, assistant volunteer clinical etc.

To watch the lecture live, log in at 4 p.m. to Free CME credit is available for the live and archived versions of this lecture. An archived version of the lecture will be posted Thursday, Aug. 18, at

For a complete webinar schedule, visit


Arrow Public health information exchange presentation

Indiana Center of Excellence in Public Health Informatics will present “Last Mile: Technical Challenges in Exchanging Data Between Clinics and Public Health” from 12:30 to 1:30 p.m. Thursday, Aug. 18, in the Health Informatics and Translational Sciences (HITS) building, room 1110.

Stephen Downs, MD, associate professor of pediatrics, associate professor of knowledge informatics and translation and director of Indiana Children’s Health Services Research, will present. Dr. Downs also is a Jean and Jerry Bepko Scholar in Pediatrics.

Anyone interested in public health informatics is welcome to attend. Lunch will be included.


Arrow Eskenazi Health Run/Walk — Sept. 10

Wishard Foundation will hold the inaugural Eskenazi Health Run/Walk and community health fair on Saturday, Sept. 10.

The event schedule includes a 5K, 1 Mile and 10K options, an opening ceremony and awards. All runs will begin between 7:15 and 7:40 a.m. and will start and end at the Ott Building of Wishard Health Services. Registration begins at 6 a.m.

The community health fair will be from 7 to 11 a.m. This event will encourage community health through preventive care and healthful diet and lifestyle choices and promote awareness of the new Sidney and Lois Eskenazi Hospital and Eskenazi Health campus opening in December 2013. 

To register, visit to register. No advance registration is required to attend and participate in the health fair.


Arrow Conference on growing non-profits

“Indiana Nonprofit Capacity Building Conference,” Indiana's premier nonprofit and community leadership conference, will be from 8 a.m. to 4:30 p.m. Wednesday, Sept. 28, in the IUPUI Campus Center.

This annual, one-day event welcomes nonprofit and community leaders to network, share best practices, and learn from experts and peers. Tarik Glenn, co-founder and chair of D.R.E.A.M. Alive, Inc., Superbowl champion and retired offensive lineman for the Indianapolis Colts, will be the keynote speaker.

This event is sponsored by SAVI and the IUPUI Solutions Center. Register is $100 per person until Tuesday, Sept 6. Late registration (Sept. 7-19) is $135.

For more information, visit


News to Use

Arrow IUPUI Regatta team registration — Aug. 15

Team registration for the third annual IUPUI Regatta, the campus’ annual boat race on the downtown canal, will open Monday, Aug. 15. Alumni, faculty, staff and students are welcome to participate in this new campus tradition Saturday, Sept. 24.

Teams can include all students or any mix of alumni, faculty, staff and students (at the alumni, faculty, and staff price). Registration will remain open until Friday, Sept. 9. To sign up, visit

Additional Regatta attractions will include live bands, face painters, local food vendors, dog shows and clowns. Campus events leading up to the event will take place Sept. 19-23, including a Greek battleship contest, concerts and a gladiator water balloon competition.

For more information, visit the Facebook page at or follow the event on twitter at

The IUPUI Regatta is presented by Herff Jones.


Arrow Bicycling program registration open

IUPUI Work/Life Balance and Bicycle Garage Indy are partnering to bring a new bicycling program to faculty, staff and students.

This program encourages participants to bike 150 miles anytime, anywhere between Aug. 22-Oct. 2 and includes several optional learning sessions on stretching, hydration, how to structure your bike workout, cadence, shifting, safety, rules of the road, etiquette and more. A kick-off event will be from 7:30 a.m. to 5:30 p.m. Friday, August 19, in front of Taylor Hall.

Sign up by Friday, Aug. 12, at The cost is $22.95 and includes a bicycle computer, safety check, workshops and other perks.

For more information, visit

Questions to Maggie Stimming at 274-5466.


Arrow Trustees to meet Aug. 18-19

The next meeting of the IU Board of Trustees will be Aug. 18-19 at the University Place Hotel and Conference Center. Subjects under discussion will include sports budgets, employee retirement plans and academic quality metrics. Trustees will also receive updates on the Ball Gardens Renovation and Eskenazi Health Land Exchange projects.

For a complete agenda, visit


Arrow This Week on Sound Medicine

This week on Sound Medicine, experts discuss eye health, including sun protection, advances in glaucoma diagnosis and treatment and eyewear for young athletes. Additional topics include heart murmurs, an alleged CIA vaccine ruse and coffee’s protective effects. Sound Medicine airs Aug. 14 and 16 on WFYI, 90.1.FM, and on many other public radio stations nationwide.

Sound Medicine is an award-winning radio program co-produced by IUSM and WFYI Public Radio. It is underwritten by IU Health Physicians and IUPUI. Reports on Primary Health Care topics are sponsored by Wishard Health Services.

For more information on this episode, visit the IUSM Newsroom. To listen online, see the Sound Medicine website.



Arrow Informatics project grants — request for applications

The Indiana Clinical and Translational Sciences Institute is offering a new grant mechanism to support sustainable and collaborative informatics projects. These awards are part of the "innovation initiatives series" within the bioinformatics program of the Indiana CTSI.

Applications require collaboration between two primary investigators from the IU schools of medicine and informatics. Additional collaborators are allowed and are not limited to these schools. This grant is open to investigators eligible to submit applications to NIH, NSF and other federal organization for funding. For additional eligibility requirements, see the complete guidelines.

Awards will be up to $100,000. All applications will be peer reviewed. Investigators selected for funding will be expected to address the reviewers concerns prior to funding.

This program is provided with support from the IU School of Informatics. There is no specific application deadline. This RFA will expire Jan. 1, 2012.

To apply, visit Questions to 278-2874 or


Arrow IU Health Values Fund Grants

2012-2013 IU Health Values Fund grants are available for Medical Research, Medical Education and the Integration of Religious and Spiritual Dimension in Health Care.

The Medical Research and the Medical Education grant application due date is noon, Monday, Oct. 17, with funding beginning in the early to mid-spring. Questions to Rob Clark at 962-9653 or

Informational sessions on Medical Research will be available from 9:45 to 11:15 a.m. Thursday, Aug. 25, in Methodist Hospital DG 434 or 2 to 3 p.m. Monday, Sept. 12, in the IU Simon Cancer Pavilion RT 101. Informational sessions on Medical Education will be available from 9:45 to 11:15 a.m. Tuesday, Aug. 23, in the IU Simon Cancer Pavilion RT 101, or 1:45 to 3:15 p.m. Thursday, Sept. 15, in Methodist Hospital DG 433.

Applicants for The Integration of Religious and Spiritual Dimensions in Health Care must submit a letter of interest by noon, Monday, Aug. 22. Complete applications are due by noon, Monday, Oct. 17. Funding will begin on or about March 1. Questions to Steven Ivy at or Nicole Veale at 962-3591 or

Eligible applicants include IU Health employees and IU Health medical staff, including physicians and health professionals with staff privileges at IU Health.

For more information, visit


Grants & Funding

Arrow Grants and Awards — July 2011

The following list includes new and competing research awards received during the month of July 2011, excluding commercial projects. Amounts shown are based on the first budget period/year:

PI Agency Type Project Title Begin End Total
Tomohiko Ai, MD, PhD Methodist Research Institute New The role of Ca2+ -activated small conductance K+ (SK) channels in human heart failure. 7/1/11 6/30/12 $40,000
Imranul Alam, PhD Showalter Trust New Role of Snca and Spr genes for peak bone mass and strength in mice 7/1/11 6/30/12 $51,000
Tracy G. Anthony, PhD NIH-NICHD New Molecular Mechanisms of Adverse Metabolic Events by Asparaginase 7/25/11 4/30/12 $306,856
Gregory Wendell Arling, PhD University Of Minnesota New Nursing Facility Quality Measures in Pay for Performance Model 4/4/11 6/30/11 $33,461
Robert M. Bigsby, PhD NIH-NCI New Endocrine targets for prevention of lung cancer 7/6/11 6/30/12 $77,000
Dawn Marie Bravata, MD Yale University New Sleep Apnea in TIA: Reducing Cardiovascular Risk with Positive Airway Pressure 9/30/10 5/31/11 $241,925
Hal E. Broxmeyer, PhD NIH-NIDDK Contin/
Regulation of Hematopoietic Cell Production 7/1/11 6/30/12 $388,594
Angelo Manuel De Almei Cardoso, MD, PhD Showalter Trust New Microenvironment-Triggered Signals Critical for T-cell Leukemogenesis 7/1/11 6/30/12 $60,000
D. Wade Clapp, MD Children's Tumor Foundation New Drug Discovery Initiative Neurofibromatosis Preclinical Consortium 7/1/11 6/30/12 $150,000
Timothy William Corson, PhD Knights Templar Eye Fdn New Screening for KIF14 Inhibitors: a Novel Retinoblastoma Therapeutic Strategy 7/1/11 6/30/12 $40,000
Theodore R. Cummins, PhD NIH-NINDS Contin/
Sodium channels and electrogenesis in sensory neurons 7/1/11 6/30/12 $334,050
Michael J. Econs, MD NIH-NIA New Identification of genes that affect peak BMD in men and women 7/1/11 6/30/12 $592,750
Loren J. Field, PhD NIH-NHLBI New Cell cycle activation for cardiac repair 7/15/11 5/31/12 $385,000
Loren J. Field, PhD American Cancer Society New Molecular dissection of acute vs. chronic DOX-induced cardiotoxicity 7/1/11 6/30/12 $50,000
Anthony B. Firulli, PhD NIH-NIAMS New The role of Twist family bHLH factors in limb morphogenesis 7/1/11 6/30/12 $346,500
Shekhar Raja Gangaraju, PhD Showalter Trust New Adipose Stromal Cells and Vascular Repair in Diabetic Retinopathy 7/1/11 6/30/12 $60,000
David Paul Gilley, PhD Avon Foundation New Targeting telomere dysfunction for early breast cancer detection 7/1/11 6/30/12 $150,000
Richard Brian Gunderman, MD, PhD American Roentgen Ray Society New ARRS/Leonard Berlin Scholarship in Medical Professionalism 7/1/11 6/30/12 $50,000
Peter Celestine Hollenhorst, PhD Showalter Trust New The role of AP-1 in the specific function of oncogenic ETS transcription factors 7/1/11 6/30/12 $60,000
Leslie Ann Hulvershorn, MD National Alliance for Research on Schizophrenia New Neural Mechanisms of MPH Treatment of Emotion Regulation in SMD 7/15/11 7/14/12 $30,000
Thomas Daniel Hurley, PhD NIH-NIDDK New Structural Determinants of Glycogen Synthase Regulation 7/1/11 5/31/12 $379,715
Thomas S. Inui, MD Walther Cancer Foundation New The IU Simon Cancer Center (IUSCC) AMPATH-Oncology Institute (AOI): An Exemplar of Care for the Developing World and a Population-based Research Environment for IUSCC 7/1/11 6/30/14 $1,200,000
Rolf Peter Kreutz, MD Methodist Research Institute New Genetics and Cardiac Stress Testing - The Krannert CardioBioBank (GENCAST Study) 7/1/11 6/30/12 $40,000
Raghavendra G. Mirmira, MD, PhD Am Heart Midwest New The Role of Deoxyhypusine Synthase in Pancreatic Beta Cell Stress Response 7/1/11 6/30/12 $26,000
Carmella Evans-Molina, MD, PhD Showalter Trust New Mechanistic Aspects of Calcium Homeostasis in the Diabetic Islet Beta Cell 7/1/11 6/30/12 $60,000
Amber Lee Mosley, PhD Showalter Trust New The regulation of transcription termination by RNA Polymerase II phosphorylation 7/1/11 6/30/12 $60,000
Eun Jin Oh, PhD Showalter Trust New Regulation of Syntaxin 4 and its role in glucose homeostasis and longevity 7/1/11 6/30/12 $60,000
R. Mark Payne, MD American Heart Midwest New Identification and Characterization of Altered Cardiac Mitochondrial Acetylation in Friedreich's Ataxia Cardiomyopathy 7/1/11 6/30/12 $26,000
Irina Petrache, MD NIH-NHLBI Contin/
Ceramide-induced lung destruction in emphysema 7/1/11 3/31/12 $381,561
Daniela Nicoleta Petrusca, PhD American Lung Association New The crosstalk between autophagy and efferocytosis in cigarette smoke-exposed alveolar macrophages 7/1/11 6/30/12 $40,000
Beth Rene Pflug, PhD U.S. Army Medical Research And Materiel Command New Translocator Protein Function in Castration-Resistant Prostate Cancer 7/1/11 6/30/14 $678,526
Anh-Danh Thi Phan, MD IU Health New Structural changes in the eye of patients with concurrent macular degeneration and glaucoma 5/1/11 4/30/12 $50,000
Lilian Irene Plotkin, PhD Showalter Trust New Opposing actions of mechanical forces and glucocorticoids in bone 7/1/11 6/30/12 $60,000
Brian C. Samuels, MD, PhD American Health Association Foundation New Hypothalamic Control of Translaminar Pressure Gradients 7/1/11 6/30/13 $100,000
Andrew J. Saykin, OD NIH-NIA New Estrogen and Memory: Genetic Variation and Neuroimaging 7/1/11 6/30/12 $28,760
Sarita Sehra, PhD Showalter Trust New Role of periostin in regulating goblet cell metaplasia 7/1/11 6/30/12 $60,000
Rebecca Anne Shilling, MD American Lung Association New Mechanisms of IL-17 Mediated Lung Transplant Obliterative Bronchiolitis 7/1/11 6/30/12 $40,000
Ally-Khan Badrudin Somani, MD, PhD Dermatology Foundation Contin/
Protective effects of dermal rejuvenation on photocarcinogenesis 7/1/11 6/30/12 $55,000
Lisa K. Staten, PhD Walther Cancer Foundation New Infrastructure development to expand cancer prevention and survivorship through community engagement 7/1/11 6/30/14 $900,000
William J. Sullivan Jr., PhD American Heart Midwest New Translational Control and Reactivation of the Heart Parasite Toxoplasma gondii 7/1/11 6/30/12 $50,048
William Michael Tierney, MD Regenstrief Institute Contin/
Regenstrief 44-825-70 7/1/11 6/30/12 $622,711
Raj K. Vuppalanchi, MD American College of Gastroenterology New Electrical stimulation cramp threshold frequency- a novel tool to assess skeletal muscle cramps severity in patients with cirrhosis 7/1/11 6/30/12 $34,300
Ronald C. Wek, PhD American Heart Midwest New Mechanisms Governing PERK control of ATF6 during the unfolded protein response 7/1/11 6/30/12 $26,000
Ronald C. Wek, PhD Showalter Trust New Translation and Stress Regulatory Pathways in Health and Disease 7/1/11 6/30/12 $60,000
Clark David Wells, PhD NIH-NCI New Regulation of Mammary Cell Proliferation by Apical Polarity Proteins 7/1/11 4/30/12 $312,953
Yan Xu, PhD NIH-NCI New Role of immune cell OGR1 in prostate cancer development and the mechanisms involved 7/5/11 4/30/12 $418,724
Mervin Clem Yoder, MD American Heart Midwest New Directed Differentiation of iPS Cells Into Reparative Proliferative Endothelium in Patients with Critical Limb Ischemia 7/1/11 6/30/12 $46,796
Andy Qigui Yu, MD, PhD Showalter Trust New An immune-based approach for combating cell-bound HIV-1 7/1/11 6/30/12 $60,000


Arrow Research Funding Update

The IU Office of the Vice Provost for Research and the Office of the Vice Chancellor for Research offers weekly digests containing information about funding opportunities including those that limit the number of allowable pre-proposal or proposal submissions.

OVPR and OVCR provide separate funding updates categorized by the limited submissions, sciences, social sciences, arts and humanities, technology and multidisciplinary. They include:       

To subscribe to these updates by email, visit this page.



Arrow IUSM state fair artists

IUSM faculty and staff were among the local artists honored for their creative work at the 2011 Indiana State Fair Juried Art Competition:

Jeffrey M. Rothenberg, MD, clinical associate professor of obstetrics and gynecology, was awarded first place in the professional glass art division for his sculpture, “Fallopius,” modeled after a fallopian tube.

Eric Schoch, science writer, received third place in the black and white animal photo division for a photo of an African leopard taken on a recent trip to Kenya.


 At Your Fingertips 

Arrow Continuing Medical Education

The Continuing Medical Education office launched a new and improved website at In addition to online registration and listings of grand rounds, conferences and courses, the site provides in-depth tools and information for presenters and program developers. Included are forms, tips, links, contacts, maps, and a host of other handy resources to make it easier to participate in CME events, prepare a presentation or plan an event.


Arrow Resources

Want to find a room that has a Polycom hook-up? Need official IUSM templates for your PowerPoint presentation or poster about a guest lecturer? Check out the new “Resources For” page on the IUSM web site. Resources For is accessible from the school’s home page (; look on the right-hand side of the page.

If you have suggestions of other resources that would be beneficial and could be added to this list, contact the Office of Public and Media Relations at


Arrow MedTV

The Office of Public and Media Relations now manages the MedTV screens on the medical school campus. This closed-circuit TV system, part of the IUPUI network, presents a wonderful opportunity for faculty, staff and students to communicate events and information of interest to others. It also serves as a source for broadcasting emergency information on campus.

The MedTVs are located in public areas of the HITS building, the VanNuys Medical Science Building atrium, the Daly Center, Fesler Hall, Research II, Walther Hall (R3) and the Cancer Research Institute (R4).

Announcements from departments and offices are welcome. To display your department or office announcement on MedTV, please read the MedTV guidelines and find our online submission form at

Questions? Phone 274-7722.


Arrow Scientific Calendar online

A comprehensive listing on IUSM seminars, lectures and Grand Rounds can be accessed at the new Scientific Calendar website. To place items on the Scientific Calendar, please forward them to Kelli Diener at


Arrow Scope submission guidelines

Scope wants your news items.

The deadline for submission is 8:30 a.m. on Thursdays. Scope is published electronically and sent to faculty, staff, students, and residents on Fridays (except on holiday weekends when it is published on the following Monday).

There are three easy ways to submit story ideas or information to Scope:

  • e-mail the information to
  • mail the information to Kevin Fryling, 1110 W. Michigan, LO 401, IUPUI
  • fax your information to (317) 278-8722

Contributions submitted by e-mail should be forwarded in 12 point, plain text format. Word document attachments in lieu of fliers are encouraged.

In the interest of accuracy, please do NOT use:

  • acronyms
  • abbreviations
  • campus building codes (use full, proper name of building and include the room number)
  • Dr. as a preface before names (designate MD or PhD)

To keep the electronic version of Scope as streamlined as possible, only seminars and lectures of general or multidisciplinary interest will be included.