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IUSM Scope

June 10, 2011
Volume 15 Number 22 • Indianapolis, Indiana

Topics this issue:

Above the Fold

Arrow Medical education expands to Richmond

Students pursuing a medical degree at IUSM can now complete more of their third-year—and soon fourth-year—required clinical clerkships Richmond due to a collaboration between IUSM, IU-East and Reid Hospital and Health Care Services.

This new partnership, which begins this summer, will encourage more physicians to practure in the east central Indiana area by creating more educational opportunities for medical students in the region and stronger connections to the local community. IU medical students have had the opportunity to participate in clinical clerkships in Richmond in the past, but as of June 10, the number and variety of experiences offered at Reid Hospital will expand.

Five of the required clinical clerkships will initially be offered by Reid Hospital. These clinical experiences will include obstetrics/gynecology, pediatrics, family medicine, internal medicine and emergency medicine. In the future, rotations in neurology, psychiatry, anesthesiology, surgery, radiology and medicine sub-internships will be added. When fully implemented, 10-12 students could participate in clerkships during any one month.

The IUSM clinical clerkship program in Richmond will be supported by a $500,000 commitment from the Vigran Family Foundation. Additional funding is being provided by the Quigg Family Foundation and other donors, as well as financial and in-kind support from Reid Hospital and IU-East.

For more information, visit the IUSM Newsroom.


Faculty Development & News

Arrow Yoder to lead entrepreneurship

David Wilkes, MD, executive associate dean for research affairs, and Anantha Shekhar, MD, PhD, director of the Indiana Clinical and Translational Sciences Institute, have announced that Mervin C. Yoder, MD, will be appointed assistant dean for entrepreneurial research, IU School of Medicine, and an associate director at the Indiana CTSI, effective July 1.

Dr. Yoder’s first priority will be to enhance infrastructure to generate more intellectual property and to develop best practices to increase disclosures and patents via working directly with faculty and serving as the IUSM liaison to the Indiana University Research and Technology Corporation (IURTC). He will work to develop close advisory/partnering relationships with the IU School of Law and the Kelley School of Business as well as Purdue University and the University of Notre Dame.

Dr. Yoder will retain his current appointments as Richard and Pauline Klingler Professor of Pediatrics, professor of biochemistry  and molecular biology,  adjunct professor of cellular and integrative physiology, director of the Herman B Wells Center for Pediatric Research and vice-chair for basic research in the Department of Pediatrics


Arrow Rhodes to join IUPUI

Simon Rhodes, associate dean for graduate studies and professor of cellular and integrative physiology, biochemistry, and molecular biology, will become dean of the IUPUI School of Science, effective July 1.

Bart Ng, acting dean of the IUPUI School of Science, will depart Sept. 30 to serve as the dean of the College of Science at Benedictine University in Lisle, Ill., near Chicago.


Student Showcase

Arrow Student sale to support medical missions

The Medical Mission Student Interest Group is selling candles to support healthcare provision in disadvantaged communities.

The Medical Mission SIG includes health care professionals from IUSM and the IU Health Network who work with hospitals and patients in disadvantaged communities around the world. The fundraiser is being conducted in partnership with the Timmy Foundation, a non-profit organization that utilizes student and medical volunteers to increase access to healthcare and education both domestically and abroad.

The candles, made by Indiana-based Celestial Candles, are soy based with lead free wicks. The candles being sold are pumpkin pie, candy cane, apple cinnamon, vanilla, Macintosh, strawberry sorbet and Christmas tree. The cost is $12 each. To order, contact Pich Seekaew at

For more information, visit


Events & Lectures

Arrow Teleseminar on deep learning

Linda Nilson, PhD, and Terri Tarr, PhD, will present “The Mind Has a Mind of Its Own: Teaching and Learning That's In Sync with the Mind” from noon to 2 p.m. Tuesday, June 21, in Fairbanks Hall, room 5005.

This event includes a teleseminar with Linda Nilson, PhD, director of teaching effectiveness and innovation at Clemson University, who will share teaching and learning methods and activities that enhance learners’ deep learning, retention, and retrieval, followed by a face-to-face conversation about how the ideas could fit into the IUSM curriculum.

Lunch is included. Polycom will not be available. To register, visit


Arrow Session on small biotech careers

A session on “Careers with Small Biotech Companies” will be from 10 a.m. to noon Wednesday, June 15, in the Van Nuys Medical Science Building, room 311 A/B.

This event will review career options with small biotech companies, and the ins and outs of working in them. Speakers include Coleen Carroll, PhD, assistance laboratory director at AIT Laboratories, and Sri Subramaniam, PhD, research operations manager at CS Keys.

This event is presented by the Office of Postdoctoral Affairs. To register, visit


Arrow Workshop on state-of-the-art microscopy

Mickael Sturek, PhD, and Kenneth Dunn, PhD, will be among the presenters at the Multimodal Nonlinear Optical Microscopy Workshop from Thursday, July 14, to Saturday, July 16, at the Weldon School of Biomedical Engineering at Purdue University.

This is workshop will be the first to highlight nonlinear optical microscopy in a one-day symposium, including practicum workshops with state-of-the-art microscopes, including a hands-on training session Friday, July 15, and opportunities to test samples on Saturday morning, July 16. Dr. Sturek, chair and professor of cellular and integrative physiology, will present “Bond-selective Imaging of Atherosclerosis.” Dr. Dunn, associate professor of medicine and biochemistry and molecular biology, will present “Multiphoton Microscopy for In Vivo Imaging.” Additional presenters will include microscopy experts from Harvard University, Cornell University and Purdue University.

The registration deadline is Friday, June 17. This workshop is sponsored by Purdue University Weldon School of Biomedical Engineering, Bindley Bioscience Center, Olympus Inc., Coherent and Newport/Spectra-Physics.

For more information, visit


Arrow Scholarship of teaching workshop

Valerie Dean O'Loughlin, PhD, associate professor of anatomy and cell biology and director of undergraduate studies for the medical sciences, will present an online session on “Developing a Publishable Scholarship of Teaching” from noon to 1:30 p.m. Wednesday, June 15.

Dr. O'Loughlin will discuss the ways in which she has used her anatomy classes in developing her own pedagogical research. She will discuss factors to consider in performing this type of research, and participants will leave with a specific working hypothesis to test in their classrooms, a basic understanding of what assessments can be used to test the hypothesis and a better idea about how to document their findings.

To register, visit


Arrow Memory University to present fourth workshop

The third session of the 2011 Memory University, “Managing Challenging Behaviors" will be from 1:30 to 2:30 p.m. Thursday, June 16, in the Riley Outpatient Center auditorium.

This session will be presented by Waqar Mahmud, MD, geriatric psychiatry fellow at IUSM. He will discuss strategies to assist caregivers in handling difficult behaviors in patients with Alzheimer's Disease. Dr. Mahmud has also completed fellowships in Addiction Psychiatry and Psychopharmacology at IU.

Memory University is presented by the Indiana Alzheimer Disease Center and the Alzheimer’s Association of Greater Indiana. Registration is free and begins at 1 p.m. the day of the event. To register, contact 274-493 or

For more information, see the event brochure at


Arrow Inaugural Young Professional’s Networking Event

IUSM alumni, residents and fellows in Indianapolis are invited to join D. Craig Brater, dean of the IU School of Medicine, for IUSM’s first Young Professional’s Networking Event from 5:45 to 7:15 p.m. Thursday, June 23, at Tomlinson Tap Room.

Located in the Indianapolis City Market on Market Street, Tomlinson Tap Room is one of Indy’s newest hotspots with an eclectic yet intimate vibe. 

This event is hosted by the Young Professional’s Committee of the IUSM Alumni Association. To RSVP, email name and position (resident/fellow and department) to

Questions to Missy Spurr, MD, at or Jayme Little at 2740-1345 or


Arrow Komen for the Cure tissue donation — June 25

The Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center will collect breast tissue samples from 8:30 a.m. to 2:30 p.m. Saturday, June 25, in the Hematology Clinic and Women's Center on the second floor of the IUSCC.

The Komen Tissue Bank is the only healthy breast tissue bank in the world. To register, contact Kathi Ridley at 274-2366 or or visit Donors must have a confirmed appointment time.

For more information, visit the IU Newsroom.


Arrow Scientific Writing from the Reader's Perspective

George Gopen, JD, PhD, will present a two-day workshop from 8 a.m. to 5 p.m. Monday, June 27, and Tuesday, June 28, in the Walther Hall (R3) auditorium, room 203.

“Scientific Writing from the Reader's Perspective” will focus on improving faculty’s ability to get published by improving their writing skills. Dr. Gopen is a professor of the practice of rhetoric a senior lecturing fellow in English and law at Duke University. He is a pioneer in the field of scientific writing with clients at the NIH, FDA, Bristol-Myers Squib, Bayer and Duke University School of Medicine.

Registrants must be able to commit to both days of this workshop. To sign up, visit

This event is sponsored by the IUSM Office of Faculty Affairs and Professional Development, the Indiana Clinical and Translational Science Institute (CTSI) and the IUPUI Office of the Vice Chancellor for Research.


Arrow Workshop on methamphetamine addiction

The Indiana Public Health Training Center will host a half day workshop entitled “Meth: The User, Community, and Environmental Issues” from 9 a.m. to 12:30 p.m. Wednesday, June 29, at the IUPUI Campus Center.

Topics to be covered include working with meth users, current research and statistics in Indiana, and environmental hazards and cleanup procedures associated with methamphetamine use. Registration is $35 and includes all materials, breakfast, break service and parking.

To sign up, visit


News to Use

Arrow Total compensation statement now online

Full-time IU employees may now access their total compensation statement online through the Employee Center in OneStart.

This compensation statement includes all benefits in addition to base salary and wages, including social security contribution, IU Retirement Plan or PERF retirement, Medicare contribution, medical coverage, dental coverage, life insurance and the IU Tuition Benefit. This information is refreshed from the HRMS system weekly.

To access the Employee Center, log into OneStart at, navigate to the Services tab, and click on the Employee Center section on the left sidebar.


Arrow Garden on the Go volunteers needed

Volunteers are needed for “Garden on the Go,” a mobile produce truck that brings fresh affordable produce to residents of 12 underserved Marion County neighborhoods that lack direct access to the fruits and vegetables necessary to eat properly and to maintain a healthy diet. The Garden on the Go truck stops each week at these urban “food deserts,” including senior and public housing, at the same day and time each week, year round.

Volunteers are needed each week at every stop to assist with setup, helping shoppers get on and off the truck safely, choosing produce, answering questions, and bagging and checking out. All shifts are 1.5 hours in length. Available times include 10:30 a.m., 1:30 p.m. and 4:30 p.m. Wednesdays through Sundays.

Garden on the Go is a partnership between IU Health and Green B.E.A.N. Delivery.

For more information, visit


Arrow INShape IUPUI offers personal trainers

INShape IUPUI is offering five weeks of personal training (10 sessions) from senior-level physical education students to all IUPUI faculty, staff and students interested in reaching their fitness goals.

For more information, visit

Questions to Jessica Velotta at


Arrow This week on Sound Medicine

This week on Sound Medicine, guests will examine challenges faced by young adults with autism as they leave home for college or the working world. Other discussions on the show will focus on an alternative to bypass surgery, and a new psychological research area, self-compassion. Sound Medicine airs June 11 and 12 on WFYI, 90.1FM, and on many other public radio stations nationwide.

Sound Medicine is an award-winning radio program co-produced by the Indiana University School of Medicine and WFYI Public Radio (90.1FM). Sound Medicine is underwritten by Indiana University Health, Indiana University Health Physicians, and Indiana University-Purdue University Indianapolis. Reports on Primary Health Care topics are sponsored by Wishard Health Services.



Arrow Cancer training program – application deadline June 15

Pre-doctoral students are invited to apply to the Cancer Biology Training Program (CBTP), an interdisciplinary training environment supported by the IU Simon Cancer Center for students who wish to pursue a career in cancer research.

The CBTP is designed to enhance the training received in any individual laboratory or department. Trainees are exposed to a broad range of cancer-related research encompassing both basic and clinical aspects of the disease.

Application deadline is Wednesday, June 15. For additional information about the program, visit

Questions to Dr. Hari Nakshatri at 278-2238 or


Arrow Gold Humanism Honor Society nominations

The IUSM chapter of the Gold Humanism Honor Society is accepting letters of recommendation for Class of 2012 students and residents who have shown exceptional interpersonal skills with colleagues, faculty and patients, and a caring approach to the practice of medicine, including service to the community. 

To write a letter of recommendation for one or more fourth-year students, email student names to To nominate a resident, email Linda Bratcher at A letter briefly describing the student’s performance and character, as well as why they should be inducted, is also appreciated. The nomination deadline is Wednesday, June 22.

For more information about the selection process or how to become a member of the selection team, contact Ann Zerr, MD, chapter committee chair, at or Jerry Rushton, MD, graduate committee chair, at

Additional details at


Arrow Merilyn Hester Scholarship — request for applications

The IU Simon Cancer Center Merilyn Hester Scholarship is seeking applications from students who have a strong academic record, an outstanding character, and well-defined professional goals.

This fund was created to assist medical and/or PhD students pursuing degrees in biomedical sciences and who have demonstrated an interest and potential for conducting pediatric hematology or oncology research.

Awardees will be asked to submit a final one page summary documenting what the funding has meant to them, signed by their mentor. Funding is typically $8,000 a year with the number of awardees determined by the quality of applications and available funds in a given year.

For more information, download the complete application. Submission deadline is Friday, July 1.

Questions to Julie Driscol at 274-8909 or


Arrow Fairbanks Institute pilot project proposals

Researchers affiliated with academic institutions and not-for-profit organizations are invited to apply for access to DNA and linked clinical data from INbank, a resource created by the Fairbanks Institute for Healthy Communities for research related to chronic diseases of aging.

For more information, see the complete submission guidelines. There is no application deadline. Submit proposals to Cynthia Helphingstine, PhD, president and CEO of the Fairbanks Institute, at

Questions to 238-2459 or


Grants & Funding

Arrow Grants and Awards — May 2011

The following list includes new and competing research awards received during the month of May 2011, excluding commercial projects. Amounts
shown are based on the first budget period/year:

PI Agency Type Project Title Begin End Total
Matthew C. Aalsma, PhD
HRSA New Arrested Youth: Epidemiological, Mental Health Care, and Cost-effectiveness Research to Guide Public Health Partnerships 2/1/11 1/31/12 $273,818
John Philip Breinholt III, MD
IU Health New Bioabsorbable Stents for Interim Relief of Pulmonary Artery Stenosis in a Pre-clinical Pediatric Model 5/1/11 4/30/12 $49,924
John Mitchell Chirgwin, PhD
US Dept Of Defense New Osteocyte FGF23 and resistance of bone metastases to vitamin D therapies 9/1/10 8/31/11 $115,380
Kai-Ming Chou, PhD
NIH-NCI New DNA Lesion Bypass Polymerases and Therapeutic Compounds 5/1/11 4/30/12 $16,120
David Wade Clapp, MD
NIH-NCI New Neurofibromatosis type 1 Gene Regulates Myelopoiesis 3/1/11 2/29/12 $22,360
Mary Kathryn Coe, PhD
University of Chicago New The Cultural Embeddedness of Virtue and Forgiveness 3/9/11 2/29/12 $101,810
Michael J. Econs, MD
NIH-NIAMS New The Effects of Iron Status on FGF23 Metabolism and Bone Health. 4/1/11 2/29/12 $207,900
Signe Maria Elisabet Finnell, MD
IU Health New Prioritization of Preventive Pediatric Interventions 5/1/11 4/30/12 $50,000
Evan L. Fogel, MD
University of Michigan New A Prospective, Randomized, Controlled Trial of Rectal Indomethacin in the Prevention of Post-ERCP Pancreatitis in High Risk Patients 4/1/11 2/28/12 $43,932
Theresa Ann Guise, MD
NIH-NCI New Differential TGF-? Signaling in the Bone Microenvironment: Impact on Tumor Growth 4/7/11 3/31/12 $551,442
Anita Nijhawan Haggstrom, MD
Medical College Wisconsin New Safety and Efficacy of Combination Therapy of Steroids and Propranolol vs. Propranolol Alone for the Treatment of Complicated Infantile Hemangiomas 4/1/11 3/31/12 $18,667
Chunyan He, OD
V Foundation for Cancer Research New Genetic Variants, microRNA Expression and Breast Cancer 5/1/11 4/30/12 $100,000
Monica Louise Hulbert, MD
IU Health New Integrated Approach to Pathway Dysregulation During Vaso-Occlusive Crisis in Sickle Cell Disease. 5/1/11 4/30/12 $50,000
Mark R. Kelley, PhD
NIH-NCI New The Role of Ape1 in Neurotoxicity of Cancer Treatments 2/1/11 1/31/12 $17,886
Hyun-Suk Lim, PhD
U.S. Army Medical Research & Materiel Command New Direct inhibition of Skp2 for the Treatment of Advanced Prostate Cancer 5/1/11 4/30/12 $115,380
Debra Kathleen Litzelman, MD
IU Health New Enhancing Personal and Institutional Professionalism at Clarian through Education in Behavioral and Social Science-Informed Patient-Care Practices 5/1/11 4/30/12 $49,976
Carmella Evans Molina, MD, PhD
Central Society for Clinical Research New CSCR Early Career Development Award 1/1/11 12/31/11 $10,000
Richard Michael Nass, PhD
Vanderbilt University


Mechanisms of Manganese Neurotoxicity 1/1/11 12/31/11 $58,109
Kenneth R. Olson, PhD
NSF New Hydrogen Sulfide: A Primal Oxygen Sensor 4/1/11 3/31/12 $150,000
Kamnesh Ratnakar Pradhan, MD
IU Health New Validation of Novel Biomarkers of Tumor Induced Angiogenesis in Childhood Cancer 5/1/11 4/30/12 $50,000
Jamie Lynn Renbarger, MD
NIH-NICHD New Postdoctoral Research Training in Pediatric Clinical and Developmental Pharmacology 5/1/11 4/30/12 $125,900
Andrew J. Saykin, OD
Northern California Institute For Research & Education New Alzheimer's Disease Neuromaging Initiative 9/30/10 8/31/11 $46,919
Frank P. Schubert, MD
RTI International New Sleep disturbance and the risk for adverse pregnancy outcomes 12/1/10 12/31/11 $26,739
Michael Stephen Sturek, PhD
Purdue University New Improved Therapeutics for Drug Eluting Stents 5/1/11 3/31/12 $38,095
William J. Sullivan Jr., PhD
NIH-NIAID New Stress responses in the AIDS opportunistic parasite Toxoplasma gondii 5/1/11 4/30/12 $54,734
Yang Sun, MD, PhD
Am Glaucoma Society New Oculocerebral renal syndrome of Lowe: novel role of inositol signaling in glaucoma pathogenesis 3/1/11 3/31/12 $40,000
Naomi Beth Swiezy, PhD
IU Health New Developing and Implementing an Evidence-Based Training Program for Medical Professionals to Support Quality Care for Individuals With an Autism Spectrum Disorder 5/1/11 4/30/12 $50,000
Terry A. Vik, MD
St. Jude Children's Res Hosp Contin
Childhood Cancer Survivor Study 12/1/10 11/30/11 $4,139
Xiao-Ming Xu NIH-NINDS New Grafting genetically-modified Schwann cells into a clinically-relevant SCI model 2/4/11 2/3/12 $31,334
Mervin Clem Yoder, MD
Children's Hospital Medical Center of Cincinnati New Cincinnati Cell Characterization Core 2/1/11 4/30/11 $10,695
Zhong-Yin Zhang, PhD
NIH-NCI New Structure/Function of Protein Tyrosine Phosphatases 12/1/10 11/30/11 $85,161
Zhong-Yin Zhang, PhD
NIH-NCI New Targeting PRL Phosphatases for Cancer Therapy 12/1/10 11/30/11 $21,932


Arrow Research Funding Update

The IU Office of the Vice Provost for Research and the Office of the Vice Chancellor for Research offers weekly digests containing information about funding opportunities including those that limit the number of allowable pre-proposal or proposal submissions.

OVPR and OVCR provide separate funding updates categorized by the limited submissions, sciences, social sciences, arts and humanities, technology and multidisciplinary.

Digests are sent on Wednesday and Thursday: They include: 



Arrow Six faculty named to Who's Who list

Six IUSM faculty are listed in the 2011 Indianapolis Business Journal “Who’s Who in the Life Sciences,” which highlights the “influential players,” whether in the public eye or behind the scenes, who fuel the life sciences in Indiana. They are:

  • D. Craig Brater, MD, dean of the IU Medical School, vice president of university clinical affairs, Walter J. Daly Professor of Medicine and professor of pharmacology and toxicology.
  • Kenneth Cornetta, MD, Chair and Joe C. Christian Professor of Medical and Molecular Genetics and professor of medicine and microbiology and immunology.
  • Keith March, MD, PhD, Cryptic Masons Medical Research Foundation Professor of Vascular Biology Research and professor of medicine and cellular and integrative physiology.
  • Anantha Shekhar, MD, PhD, associate dean for translational research, director of the Indiana CTSI, Raymond E. Houk Professor of Psychiatry and professor of neurobiology and pharmacology and toxicology.
  • William Tierney, MD, associate dean for clinical effectiveness research, Sam Regenstrief Professor of Health Services Research and professor of medicine.
  • David Wilkes, MD, executive associate dean for research affairs, August M. Watanabe Professor of Medical Research and professor of medicine, microbiology and immunology, and biochemistry and molecular biology.


 At Your Fingertips 

Arrow Continuing Medical Education

The Continuing Medical Education office launched a new and improved website at In addition to online registration and listings of grand rounds, conferences and courses, the site provides in-depth tools and information for presenters and program developers. Included are forms, tips, links, contacts, maps, and a host of other handy resources to make it easier to participate in CME events, prepare a presentation or plan an event.


Arrow Resources

Want to find a room that has a Polycom hook-up? Need official IUSM templates for your PowerPoint presentation or poster about a guest lecturer? Check out the new “Resources For” page on the IUSM web site. Resources For is accessible from the school’s home page (; look on the right-hand side of the page.

If you have suggestions of other resources that would be beneficial and could be added to this list, contact the Office of Public and Media Relations at


Arrow MedTV

The Office of Public and Media Relations now manages the MedTV screens on the medical school campus. This closed-circuit TV system, part of the IUPUI network, presents a wonderful opportunity for faculty, staff and students to communicate events and information of interest to others. It also serves as a source for broadcasting emergency information on campus.

The MedTVs are located in public areas of the HITS building, the VanNuys Medical Science Building atrium, the Daly Center, Fesler Hall, Research II, Walther Hall (R3) and the Cancer Research Institute (R4).

Announcements from departments and offices are welcome. To display your department or office announcement on MedTV, please read the MedTV guidelines and find our online submission form at

Questions? Phone 274-7722.


Arrow Scientific Calendar online

A comprehensive listing on IUSM seminars, lectures and Grand Rounds can be accessed at the new Scientific Calendar website. To place items on the Scientific Calendar, please forward them to Kelli Diener at


Arrow Scope submission guidelines

Scope wants your news items.

The deadline for submission is 8:30 a.m. on Thursdays. Scope is published electronically and sent to faculty, staff, students, and residents on Fridays (except on holiday weekends when it is published on the following Monday).

There are three easy ways to submit story ideas or information to Scope:

  • e-mail the information to
  • mail the information to Kevin Fryling, 1110 W. Michigan, LO 401, IUPUI
  • fax your information to (317) 278-8722

Contributions submitted by e-mail should be forwarded in 12 point, plain text format. Word document attachments in lieu of fliers are encouraged.

In the interest of accuracy, please do NOT use:

  • acronyms
  • abbreviations
  • campus building codes (use full, proper name of building and include the room number)
  • Dr. as a preface before names (designate MD or PhD)

To keep the electronic version of Scope as streamlined as possible, only seminars and lectures of general or multidisciplinary interest will be included.