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IUSM Scope



October 3, 2008
Volume 12 Number 40 • Indianapolis, Indiana

Topics this issue:



Arrow Glick Eye groundbreaking and centennial observance

The groundbreaking ceremony for the Eugene and Marilyn Glick Eye Institute will be at 11 a.m. Tuesday, Oct. 7. The four-story, 70,000-square-foot building, which will be constructed immediately south of Coleman Hall. It will house the IU Department of Ophthalmology, which is observing its 100th anniversary.

The groundbreaking ceremony will be under a tent adjacent to the building site and immediately west of Long Hospital.

Construction of the Glick Eye Institute was made possible with a $30 million gift from the Eugene and Marilyn Glick Family Foundation. The Glick Foundation gift included $10 million to the School of Medicine to start an endowment that will advance research in eye diseases such as glaucoma, macular degeneration, diabetic retinopathy, cataracts and other eye diseases of aging, as well as eye diseases in children.

Alumni, faculty, staff, friends, and others will celebrate the centennial of the founding of the IU Department of Ophthalmology Oct. 10-12, with a medical education conference, “Advances in Ophthalmology: The Future is Here,” social events and a celebratory dinner.

For additional information on the Eugene and Marilyn Glick Eye Institute and the IU Department of Ophthalmology at the IU School of Medicine, see www.iueye.iu.edu/.


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Arrow New online listing system established for clinical trials

With the establishment of the Indiana Clinical and Translational Sciences Institute (CTSI), all clinical trials reviewed by one of the IUPUI Institutional Review Boards (IRBs) now are listed on the CTSI web site at www.indianactsi.org/clinicaltrial. As a result, listings at the IUSM Office of Clinical Research web site are no longer being updated.

The CTSI staff has been working with the Office of Research Administration to obtain IRB documentation from each research study that utilizes one of the IUPUI-IRBs. Whether a study is a new study, amended study or going through continuing review, the most up-to-date information from the following three documents will be extracted for the CTSI listing:

  1. DRA, Continuing Review or Amendment Form
  2. Summary Safeguard Statement (SSS)
  3. Informed Consent Document (ICD)

As a result of these changes, investigators do not need to fill out separate forms to have their studies listed on the web site. The CTSI staff will extract the information and the listings will be updated on a biweekly basis as the updated documents are received from the IRB.

Studies that have not submitted information recently to the IRB may not have been listed yet on the CTSI web site. Investigators who would like to have their studies listed can fill out this document: www.indianactsi.org/site/clinicaltrialsform.doc.

For additional information contact Emily Hardwick, CTSI coordinator of research subject recruitment, at ejhardwi@iupui.edu.

The CTSI was established in May with a five-year, $25 million award from the National Institutes of Health.


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Arrow Call for posters for first Indiana CTSI meeting

The Indiana Clinical and Translational Science Institute will host its first annual Indiana CTSI meeting on Thursday, Nov. 20. This new NIH-funded research institute is a partnership between IUPUI, Indiana University-Bloomington, and Purdue University, and has research training, education, and career development of fellows and junior faculty as one of its major goals.

Keynote speakers will include Gov. Mitch Daniels and Barbara Alving, MD, director of the NIH’s National Center for Research Resources, as well as research leaders from across Indiana.

As part of the program, the CTSI will host a poster session to showcase the research of predoctoral and postdoctoral trainees as well as junior faculty investigators in the clinical and translational sciences. There will be a number of awards for the top predoctoral and postdoctoral posters.

Submissions from predoctoral and postdoctoral trainees and junior faculty from all campuses are encouraged. If interested, send the title of your poster, your name and affiliation by Thursday, Oct. 30, to Donna Burgett at dburgett@regenstrief.org. Questions: call 317-630-7447.


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Arrow Fall Faculty Meeting – Oct 14

The IUSM Fall Faculty Meeting will be from 3:30 to 5 p.m., Tuesday, Oct. 14, in the Riley Outpatient Center auditorium.

Featured speakers and their topics:

  • John F. Fitzgerald, M.D.
    Executive Associate Dean for Clinical Affairs
    “Indiana Clinic”
  • Roger W. Schmenner
    Chief of Staff, Office of the Chancellor, IUPUI
    “Future IUPUI Campus Changes”


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Arrow Quaid to present Research Ethics discussion

“Scientific Misconduct: Definitions, Policies, and Procedures” will be presented at 3 p.m. Wednesday, Oct. 15, in VanNuys Medical Science Building, room 326.

All IUSM postdocs and graduate students are invited but reservations are requested at the Office of Postdoctoral Affairs.

Kimberly Quaid, PhD, professor of medical and molecular genetics, co-director of the Master of Science in Genetic Counseling program and director of the Predictive Testing Program, will be the speaker.


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Arrow Clarian Leadership Ethics Lecture – Oct. 15

“The Ethics of Teamwork” will be presented by Suzanne Gordon at the ninth annual Clarian Leadership Ethics Lecture from noon to 1 p.m. Wednesday, Oct. 15, at the Methodist Hospital Petticrew Auditorium.

Gordon is an award-winning journalist, playwright, and author of several books including Nursing Against the Odds, Life Support, and Complexities of Care: Nursing Reconsidered

The presentation is part of the Fairbanks Ethics Lecture Series and CME/CE credit is offered. Lunch will not be provided, but “brown bag” lunches are acceptable. For questions and comments, contact Amy Chamness at achamnes@clarian.org or 962-1721.

For additional information about the Charles Warren Fairbanks Center for Medical Ethics, please visit our website at www.fairbankscenter.org.


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Arrow Public Health Training Center hosts two fall workshops

“The CSI Approach to Strategic and Business Planning” will be led by Dr. Steve Nataro in a full day session Thursday, Oct. 16, on the basics of business for health and non-profit organizations. Dr. Nataro, who recently received the Excellence in Teaching Award at the University of Illinois Champaign-Urbana, has a wealth of experience managing non-profits and has developed this course as a way to help public health professionals succeed at the business behind the care.

Worksheets, tools, and resources will be incorporated into the day. The workshop will be from 9 a.m. to 3 p.m. at the MAPHTC Training Center, located at 714 N. Senate, Indianapolis. The $40 registration fee will cover all materials, break service, lunch, and a certificate.

Do Pregnant Women Really Need to Stay Away from Litter Boxes? This and other questions related to animals and public health will be answered by state epidemiologist and veterinarian Dr. Jim Howell and veterinarian Dr. John Schnarr at the Public Health Café on Tuesday, Oct. 21. The speakers will address common myths and demonstrate why we need to consider animal health as a public health issue.

The Café will be from 8 to 9:30 a.m. at the MAPHTC Training Center, 714 N. Senate. The program is free of charge and includes breakfast.

For those who can’t attend in person, all Public Health Cafés are available by live webstreaming. Simply indicate on the registration form that you will be viewing online to receive a specific log on and viewing instructions in a confirmation email.

To register for either program, visit www.publichealthconnect.org. Click on 'Live Programs.'

Questions or Comments? Contact Kate Nicholson, program manager, at katlnich@iupui.edu or 274-3178.


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Arrow Beering Lecture – Oct. 29

The 2008 Beering Lecture will be at 8:30 a.m. Wednesday, Oct. 29, with Charles A. Dinarello, MD, presenting. This year the event has been moved to the auditorium of the Riley Outpatient Center.

Dr. Dinarello is a professor of medicine at the University of Colorado School of Medicine. His research focus is anti-cytokin-based therapies.


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Arrow FEED workshop: Energizing your work passion

Rejuvenation: Bringing Energy and Passion to Your Work – part of the Faculty Enrichment and Education Development series – will be Wednesday, Oct. 29, from 5 to 7 p.m. in the Riley Outpatient Center conference rooms A and B. A dinner buffet will be provided.

The workshop will be presented by Stephen Bogdewic, PhD. This workshop, hosted by the IUSM Office of Faculty Affairs and Professional Development, will invite participants to reflect on what energizes them in their work. It will provide a framework for understanding the organizational culture that contributes to fun and energy at work and introduce a philosophy for applying this to every day tasks.

To register, see ctl.iupui.edu/Events/eventsCalendar.asp. CME credit awarded for attending.


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Arrow How Telling the Tale Impacts the Illness: A Free Symposium

“Cancer Stories: The Impact of Narrative on a Modern Malady,” a two-day symposium sponsored by the IU School of Liberal Arts at IUPUI and the IU School of Medicine, will be Nov. 6-8.

The symposium will be based on the premise that narratives about cancer have shaped the human and institutional response to cancer in America. Prose, poetry, performance and the visual arts constitute the range of narratives the symposium will explore. Included are both the production and reception of cancer stories by physicians, nurses, patients, artists, and advocates to explore how the cultural meaning of cancer has shaped the human and institutional response to it.

“Cancer Stories” is a free symposium. Speakers and their topics will include:

  • David Cantor, deputy director of the Office of NIH History, “Choosing to Live: Cancer Education, Movies, and the Conversion Narrative in 20th Century America”
  • Arthur W. Frank, professor of sociology at the University of Calgary, Ontario, Canada, “Telling Your Story: Narrative Illness in an Age of Authenticity and Appropriation”
  • Martha Stoddard-Holmes, associate professor of literature and writing studies, California State University, “Cancer Comix: Narrating Cancer through Sequential Art”

An independent documentary film, “A Lion in the House: The Transformative Power of Storytelling at End-of-Life” will be shown and other breakout sessions are included covering everything from scar photograph to the metaphors of living.

Visit medhumanities.iupui.edu/symposium_2008.htm for more information


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Arrow Listserv registration provides quick link to faculty programs

What is happening in faculty development? The Dean’s Office of Faculty Affairs and Professional Development has prepared an impressive list of events and programs designed to help faculty with their personal and professional development needs. Stay in the loop as these events are announced by joining the OFAPD listserv email list.

By joining, you will receive periodic emails sharing the latest news about faculty development programs and upcoming faculty development events. This list will be strictly used for this purpose and members will receive one or two emails per month.

To join the list, go to www.faculty.medicine.iu.edu and click on the “Join the OFAPD listserv” link at the top of the page. If you have any questions, contact the list owner, Sarah Reed, OFAPD program manager, at sarareed@iupui.edu


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Arrow Beginner’s Guide to grant submission now online

“The Beginner’s Guide to the Grant Submission Process at the IUSM” is now available on the Office of Faculty Affairs and Professional Development web site. The guide was written by Brenda Grimes, PhD, assistant professor of medical and molecular genetics, and Randy Brutkiewicz, PhD, professor of microbiology and immunology and assistant dean, IUSM Office of Faculty Affairs and Professional Development.

The guide is designed to help new investigators navigate the complex grant submission process. To access the guide, go to www.faculty.medicine.iu.edu and click on the faculty development link. The guide is located in the “For Research Faculty” section of the web site.


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Arrow Blood battle begins: IU-Purdue donor challenge

The 12th annual IU vs. Purdue Blood Donor Challenge begins Oct. 6 and runs through Nov. 14. This blood battle helps save lives as the two universities engage in a friendly competition to encourage Indiana residents to donate blood.

A list of participating blood donor centers can be found at alumni.indiana.edu/events/challenge/donationsites.shtml. More information on the Blood Donor Challenge, including the history of the rivalry, can be found at alumni.indiana.edu/events/challenge/.


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Arrow Timmy Foundation needs supplies, volunteers

The Purdue chapter of the Timmy Foundation seeks doctors, nurses, dentists, pharmacists and nurse practitioners interested in volunteering a week of their time in Quito, Ecuador, March 14-22. This trip is organized by a group of 18 Purdue students, who along with traveling to Ecuador in March, work to raise donations of medical supplies, over-the-counter medications, and hygiene products for this overseas work.

If you are interested in traveling abroad with us this spring, or if you would like to make a donation of medicine or medical supplies to support our cause, contact Chad Flowers at ctflower@purdue.edu. Learn more about the Timmy Foundation and our work at www.timmyfoundation.org.


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Arrow LAMP participants announced

The IUSM Leadership in Academic Medicine Program ( LAMP ) is a monthly series of workshops to facilitate academic success for a selected group of new medical school faculty.

The seminars introduce participants to the fundamentals of career planning, self-management and leadership skills. The skills and understandings developed in this program are intended to provide faculty with tools that will enable them to accomplish their primary career goals and aspirations. Participants in LAMP must be nominated by their chair or division director as a future leader in academic medicine.

Congratulations to the 2008-09 LAMP cohort members: Narasimhan Agaram, Cynthia Bodkin, John Breinholt, Jey-Hsin Chen, Jennifer Choi, Jeff Dunkle, Jason Ford, Virgilio George, Sarah Hill, Muhammad Idrees, Erin Kreb, Aaron Leary, Julia Le Blanc, John Lopshire, Naveen Machandra, Brandy Matthews, Devonne Mullis, Maria Poor, Eugene Presto, Rajashekhar Siddappa, Shivani Srivastava, Chris Strachan, Dorota Szcezpenak, Emily Webber, Elizabeth Weinstein, and Meredith Williams.


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Arrow Honors

IUSM Dean Emeritus Walter J. Daly, MD, is the 2008 recipient of the Lifetime Award for Distinguished Service in Years of Health Advancement from the Indiana Public Health Foundation. The presentation was made Oct. 2 at the Tony and Mary Hulman Health Achievement Awards Dinner.

The 2008 Dr. Kathleen Galbraith Legacy Leadership Award was presented by the Indiana State Medical Association to Rose S. Fife, MD, and Antoinette L. Laskey, MD, “for significant contributions to address issues of endangerment and violence.” This is the first year of the award, which was presented Sept. 21 at the Indiana State Medical Association House of Delegates meeting. Dr. Laskey and Dr. Fife were recognized for establishing the Family Violence Institute, housed at IUSM, which was created in 2007 to bring together key players across the state to fight family violence. Through research, education, clinical improvements and policy changes, the institute is dedicated to eliminating child abuse, domestic and workplace violence, and elder abuse.

The Radiological Society of North America has named Richard Gunderman, MD, PhD, its 2008 Outstanding Educator. The award is presented “to one senior individual each year who has made original and significant contributions to the field of radiology or the radiologic sciences throughout a career of teaching and education.” Dr. Gunderman is a professor of radiology, pediatrics, medical education, philosophy, liberal arts and philanthropy at IUPUI. He is a six-time recipient of the IU Trustees Teaching Award and he has received IUPUI’s and IU’s highest awards for teaching excellence.

Raghu G. Mirmira, PhD, MD, has been invited to serve as a member of the Diabetes, Endocrinology and Metabolic Diseases B Subcommittee of the Diabetes and Digestive and Kidney Diseases Initial Review Group at the National Institute of Diabetes and Digestive and Kidney Diseases. His term of service is from August 2008 to June 2012.


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Arrow IUSM Grants and Awards: August 2008

PI Agency Research Type Project Title Begin End Total $
Matthew Allen Showalter Trust New Effects of cancer-related bisphosphonate treatment regimens on oral surgery healing 7/1/2008 6/30/2009 59,836
Paula Braitstein Moi University Faculty of Health Sciences New The role of traditional medicine in the management of HIV and AIDS in Western Kenya 9/1/2007 8/31/2008 5,192
Darron Brown National Institute of Allergy and Infectious Diseases New HPV in Adolescent Women 7/15/2008 6/30/2009 352,500
David Burr Orthopaedic Research and Education Foundation New 38th International Sun Valley Skeletal Tissue Workshop 8/3/2008 8/6/2008 10,000
David Burr National Institute of Arthritis and Musculoskeletal and Skin Diseases New Remodeling Suppression: Collagen Effects on Fracture Energy 8/15/2008 5/31/2009 332,200
David Burr National Institute of Arthritis and Musculoskeletal and Skin Diseases New Sun Valley Workshop on Skeletal Biology 8/1/2008 2/28/2009 13,351
Angelo Manuel De Almei Cardoso St. Baldrick's Foundation New Notch modulates IL7-triggered STAT signaling in childhood T-cell leukemia 7/1/2008 6/30/2009 50,000
Rebecca Chan National Institute of Aging New Improved Therapies for AML in the Elderly 7/1/2008 6/30/2009 26,955
Hua-Chen Chang Purdue University New Immunotherapy for Non-Hodgkin's Lymphoma via Nanoparticle-Mediated Delivery System 7/1/2008 12/31/2008 14,200
Roman Dziarski National Institute of Allergy and Infectious Diseases New Mechanism of Antibacterial Activity of Peptidoglycan Recognition Proteins 7/29/2008 6/30/2009 377,750
David Flockhart National Institute of General Medical Sciences Contin/
Competing
Clinical Pharmacology Training Grant 7/1/2008 6/30/2009 177,999
Evan Fogel Medical University of South Carolina New Evaluating Predictor Intervention in Sphincter of ODDI Dysfunction (EPISOD) 9/15/2007 6/30/2008 97,791
Shreevrat Goenka Showalter Trust New Role of CoaSt6 in Allergic Asthma. 7/1/2008 6/30/2009 60,000
Susan Gunst National Heart, Lung, and Blood Institute Contin/
Competing
Regulation of actin dynamics in airway smooth muscle 7/1/2008 4/30/2009 385,000
David Haas National Institute of Child Health and Human Development New Pharmacogenetics of antenatal corticosteroids to improve neonatal outcomes 8/11/2008 7/31/2009 134,838
Johnny He National Institute on Drug Abuse New Drug abuse and NeuroAIDS in China 8/1/2008 7/31/2009 140,484
Andy Hudmon Showalter Trust New Calcium-dependent regulation of cardiac voltage-gated sodium channels: mechanisms underlying abnormal conduction in heart failure 7/1/2008 6/30/2009 60,000
Melissa Kacena Showalter Trust New Megakaryocyte-Mediated Inhibition of Osteoclastogenesis 7/1/2008 6/30/2009 59,983
Daniel Meldrum National Heart, Lung, and Blood Institute New Neonatal stem cells: Unique traits in paracrine signaling and cardioprotection 7/1/2008 6/30/2009 49,646
Daniel Meldrum National Heart, Lung, and Blood Institute New IL-18 Signaling in mesenchymal stem cells: Function and surgical protection 7/1/2008 6/30/2009 50,517
Oussama Meroueh Showalter Trust New Computer-Guided Design of Small Molecules that Block Tumor Invasion and Metastasis 7/1/2008 6/30/2009 60,000
Steven Miller American Heart Association Midwest New Novel mechanisms regulating aging-impaired arteriogenesis 7/1/2008 6/30/2009 71,500
Raghavendra Mirmira Juvenile Diabetes Foundation New Role of Set9 in Islet Development and Function. 4/1/2008 10/31/2008 149,343
Raghavendra Mirmira American Diabetes Association New Epigenetic Regulation of Insulin Gene Transcription 4/1/2008 6/30/2009 183,349
Kenneth Nephew Phi Beta Psi Contin/
Competing
Epigenetic Targeting of Ovarian Tumor Stem Cells 8/1/2008 7/31/2009 60,200
Ronald Payne Federacion Española de Ataxia New Use of TAT-Frataxin fusion protein to reverse the phenotype of Friedreich's Ataxia. 7/1/2008 6/30/2009 30,000
Irina Petrache Johns Hopkins University New Novel Protective antiapoptotic action of Alpha 1-antitrypsin in emphysema 9/14/2007 8/31/2008 268,432
David Pisoni National Institute on Deafness and Other Communication Disorders New Neurocognitive Processes in Deaf Children with Cochlear Implants 8/1/2008 7/31/2010 100,000
Greg Sachs Agency for Healthcare Research and Quality New Optimal Prevention & Treatment In Medically complex ALzheimer patients (OPTIMAL) 8/1/2008 7/31/2009 131,039
Paresh Sanghani Showalter Trust New Pharmacological and Cellular effects of S-nitrosoglutathione reductase inhibition 7/1/2008 6/30/2009 60,000
Changyu Shen Showalter Trust New A Unified Statistical Framework for High-throughput Label-free Protein Quantification Using Mass Spectrometry 7/1/2008 6/30/2009 59,968
Marcia Shew Children's Hospital of Cincinnati New Behavioral and Virologic Impact of HPV Immunization 1/15/2008 12/31/2008 87,972
Jianjian Shi Showalter Trust New Role of Rho Kinase in Diabetic Nephropathy and Cardiomyopathy 7/1/2008 6/30/2009 60,000
George Sledge, Jr. Komen Cancer Foundation New Project 1: Examination of the human kinome for novel genome-specific therapeutic targets in triple-negative breast cancer; and project 2; Association of genetic variability with receptor activation of tumor angiogenesis inhibitors: an in vitro gen 3/31/2008 3/31/2009 200,000
Robert Tepper National Heart, Lung, and Blood Institute Contin/
Competing
Modulation of Airway Reactivity by Chronic Mechanical Strain 8/1/2008 7/31/2009 390,598
Frederick Unverzagt National Institute of Nursing Research Contin/
Competing
ACTIVE PHASE III: IU Field Site 6/26/2008 4/30/2009 391,913
Mu Wang Multiple Myeloma Research Foundation New Biomarker Discovery and Validation in Multiple Myeloma Cells Using Multiple Proteomic Platforms 8/1/2008 7/31/2009 250,000
Constantin Yiannoutsos National Institute of Mental Health New National NeuroAIDS Tissue Consortium Statistics and Data Coordinating Center 8/7/2008 4/30/2009 708,573
Xin Zhang Showalter Trust New Heparan sulfate modification in lacrimal gland development 7/1/2008 6/30/2009 60,000


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Arrow This week on Sound Medicine

Tune in at 2 p.m. Sunday, Oct. 5, to Sound Medicine, the award-winning weekly radio program co-produced by IUSM and WFYI Public Radio (90.1 FM) in Indianapolis. The program is hosted by Barb Lewis.

This week, Sound Medicine will air the second in the three-part series entitled “Not If, But When.” The series will present information from national public health officials and ethicists who gathered in Indianapolis in July to discuss the ethical issues of planning and caring for the public during an influenza pandemic.

“Not If, But When” guests will look at Indiana’s preparations for an influenza pandemic.

Sound Medicine’s April Bell will discuss how clinics in the IU-Kenya Partnership were able to carry on treating patients with HIV/AIDS during the recent post-election violence in and around Eldoret, where the Moi University medical school and hospital are located.

The President’s Emergency Program for AIDS Relief , as viewed by the community of bioethicists, will be the topic of co-host Eric Meslin, PhD, director of the IU Center for Bioethics.

Morton Meyers, MD, author of Happy Accidents: Serendipity in Modern Medical Breakthroughs, will explain how current rigid research protocols are making it less likely for researchers to stumble across unexpected findings in the laboratory.

Archived editions of Sound Medicine as well as other helpful information can be found at www.soundmedicine.iu.edu.

Sound Medicine is underwritten by the Lilly Center for Medical Science, Clarian Health, and IU Medical Group. Jeremy Shere's “Check-Up” is underwritten by IUPUI.


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Arrow Continuing Medical Education at your fingertips

The Continuing Medical Education office launched a new and improved website at cme.medicine.iu.edu. In addition to online registration and listings of grand rounds, conferences and courses, the site provides in-depth tools and information for presenters and program developers. Included are forms, tips, links, contacts, maps, and a host of other handy resources to make it easier to participate in CME events, prepare a presentation or plan an event.

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Arrow Scientific Calendar online

A comprehensive listing on IUSM seminars, lectures and Grand Rounds can be accessed at the new Scientific Calendar website. To place items on the Scientific Calendar, please forward them to Kelli Diener at kas1@iupui.edu.

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Arrow Scope submission guidelines

Scope wants your news items.

The deadline for submission is 8:30 a.m. on Thursdays. Scope is published electronically and sent to faculty, staff, students, and residents on Fridays (except on holiday weekends when it is published on the following Monday).

There are three easy ways to submit story ideas or information to Scope:

  • e-mail the information to mhardin@iupui.edu
  • mail the information to Mary Hardin, Z-7, Ste. 306, IUPUI
  • fax your information to (317) 278-8722

Contributions submitted by e-mail should be forwarded in 12 point, plain text format. Word document attachments in lieu of fliers are encouraged.

In the interest of accuracy, please do NOT use:

  • acronyms
  • abbreviations
  • campus building codes (use full, proper name of building and include the room number)
  • Dr. as a preface before names (designate MD or PhD)

To keep the electronic version of Scope as streamlined as possible, only seminars and lectures of general or multidisciplinary interest will be included.

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